Prostaglandin-based serums, such as Latisse and RapidLash, are particularly noteworthy as they can prolong the duration of the growth phase, allowing lashes to grow longer than they would naturally. However, despite their remarkable effectiveness, these prostaglandins come with potential side effects, including the development of dark circles under the eyes, changes in iris color, and fat loss around the eye area, which can be concerning for many users.